Recently, the Chinese academy of agricultural sciences by using the transcriptome and proteomics approach to no FecB mutation and significant differences lambing number of small tail cold sheep uterine joint analysis, found and identified several key genes associated with sheep lamb more characters and signaling pathways, in order to further explore the molecular mechanism of high yield and sheep breeding prolific sheep breeds provides a scientific basis.

Lambing number is one of the most important reproductive traits in sheep, which is controlled by micropotent polygenes. It is always the focus of breeding scientists to find the key genes affecting lambing number. As the main place of embryo growth and development, uterine dysfunction can cause 20%~30% embryo loss, up to 40%, and embryo damage is one of the main factors affecting the number of lambs.

In this study, the single and multilamb uterine tissues of small tail han sheep without FecB mutation were studied in depth. The results showed that the expressions of ACSS3, SDSL and ENSOARP00000002929 genes were significantly different in mRNA and protein levels in single and multilamb small tail cold sheep uterus. Compared with the single lamb group, the mRNA and protein significantly upregulated in the multilamb group were mainly concentrated in energy metabolism related pathways such as sphingolipid metabolism and amino acid metabolism.

Time: 2020.08.07

Source: http://caas.cn/xwzx/kyjz/306890.html