Institute of genetics and developmental biology, Chinese Academy of Sciences soybean genome-wide latest research progress has been made, the result is not only an important role in such aspects as soybean breeding, a breakthrough of the traditional linear genome "storage" form, for the first time in the plant based on the construction of a genome graphic structure, will lead the new next-generation genomics research ideas and methods.

Traditional genomics, when describing the genome, is used to label different bases on chromosomes in linear form, and obtain the genetic information of a species based on a reference genome. However, due to the genetic variation among different individuals in a species, the expression of linear genome cannot reflect the genetic variation of different individuals at the same time, which greatly restricts the identification and analysis of the genetic variation of different individuals. Therefore, it has become an important task and frontier challenge for genomics research to construct a new type of pan-genome that includes all the genetic information of a species.

In their in-depth resequencing and population genetic analysis of soybean germplasm resources, they found that there were large genetic variations among different soybean germplasm resources, and a single or minority genome could not represent all the genetic variations of soybean population.

Team, using the latest assembly strategy on 26 soybean germplasm materials for high quality genome from scratch "assembly" and precise, and on this basis, the combination has published several genomes of soybean germplasm materials, carry out the system's genome comparison, constructs the high quality based on genome-wide graphic structure, mining of using traditional genome can't identification to big fragment structure variation.

The structural variation of CHS gene cluster in wild and cultivated soybean was the main reason of seed coat color domestication from black to yellow. SoyZH13_14G179600 genetic structure mutation led to the differences of gene expression in different germplasm materials, may be associated with regulating the green soybean iron deficiency syndrome. In addition, 15 structural variations were identified that led to the fusion of different genes, providing important clues to the development of new genes.

Time: 2020.06.19

Source: http://www.cas.cn/cm/202006/t20200619_4750594.shtml